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GI MAP February 2023
Hi B.,My GI Map result has been sent to you.
Would you mind taking a look on the next steps?
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11 Replies
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results were released to you. Feel free to upload them here for us to take a look.
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thank you B.
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Hi B. & Daniel,
Please see attached today’s GI MAP “Naveed Aslam 13.3.23 GI MAP.PDF.”
I’ve also attached previous two GI maps.
H. Pylori number has increased and other markers have worsened. I’m sorry, I’m not familiar with other bacterial markers.
Zonulin (leaky gut?) has increased for the first time. Could this be the reason why I react to whatever I eat?
Occult Blood – FIT is high for the first time, but GI consultant didn’t see anything in the colonoscopy to be of concerned. See attached. What should I do.[Naveed Aslam 22.2.23 Colonoscopy By Dr. Rehan Hairdy.pdf][Naveed Aslam 13.3.23 GI MAP.pdf][Naveed Aslam 20.10.22 GI MAP.pdf][Naveed Aslam 8.6.2.22 GI MAP.pdf]
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Hey ,
Thank you for uploading your test results!
Selective IgA
What stands out to me is the low secretory IgA (sIgA). Let me first explain what it is. sIgA is part of the gut epithelial barrier and plays an important role in the development of immune tolerance and plays an important role in balancing the normal and beneficial commensal gut organism.sIgA is low, which can lead to imbalances in the gut microbiome. sIgA also prevents pathogens to get into the bodies circulation.
The good news is, although you are still short on sIgA, the levels are higher as in 2022. Perhaps the little bit of vitamin D you have used in the past weeks/months could contribute to this. We talked about this before, so not exactly a new conclusion comes from this test particular value, but it does emphasize the importants of helping the body raising vitamin D levels. Other key nutrients that help to support the immune system are vitamin A and folate.
Zonulin
You noticed indeed that Zonulin is high. Elevations in Zonulin open the tight junctions between the cells in the gut lining making it more easy for undigested parts of stool to enter the body. These tight junctions in order to close need vitamin D as well by the way.Reducing Zonulin might give your body more protection from what happens in the gut. Therefore I would avoid gluten containing grains for now.
Bacterial Markers
Most of the bacterial markers point to some form of inflammation in the gut. Bacteroides fragilis (which is low on your most recent test) is anti-inflammatory, while high levels of Enterobacter spp, for example can contribute to inflammation. There are some clues to low stomach acid, maldigestion and SIBO on the test, which is a confirmation to what we know.Occult Blood
Elevations in occult blood occur when there is more human hemoglobin present in the stool. The colonoscopy you shared looks good, so the problem isn’t there. I am curious about the results on the `histology report. `Blood loss because of a small wound can sometimes just happen.`Other reasons why Occult blood can be elevated can be for example due to
• IBS
• Bleeding Ulcers
• Upper GI bleeds that cause iron deficiency anemiaBringing balance to the microbiome starts with bringing in the nutrients first. Treating the gut with antimicrobes result in a bigger die-off of the gut bacteria. Some of these bacteria are Gramm negative which means when they die you will be exposed to more lipopolysaccharides(LPS).
With zonulin elevated and the tight junction being open this could make you more vulnerable. Having your immune system in the most optimal condition will give you more defense and could even contribute to balancing the microbiome as well.
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Good morning Daniel and B.
H. Pylori
Do I need to address the H. Pylori as the number has increased? I need something gentle due to the gastritis.
[Naveed Aslam 22.2.23 Upper Gastroscopy Histology Report.pdf]Secretory IgA
Apart from Vitamin D, what else can I do or take as this marker has been on the low side for a while.Please remind me does this help or it contains too much of other items.
https://www.amritanutrition.co.uk/products/igg-select-75g.
I did take it, but couldn’t tolerate it, maybe due to the leaky gut.
Zonulin
Will I ever heal this? I was shocked. I’ve stopped both quinoa and millet I was only taking them as they were easy on the stomach when blended. I do take jasmine rice. It’s the only way to get other food items into the stomach without any pain, like Courgettes, pak choi, carrots, chicken thigh or white fish. It’s still painful, but not as bad without the rice. Rice is naturally gluten free right?Apart from vitamin D, is there anything else I can do. I will watch your video about leaky gut B.
Occult Blood
Due to the constipation , fresh blood is visible as my skin gets irritated. Maybe, when I provided the sample I couldn’t see it. Usually, I can. I’ve asked my GP to give me the FIT kit to repeat the test.Gastroscopy and colonoscopy didn’t show any bleeding that was visible according to the consultant.
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Hey ,
H. Pylori
Even if H. Pylori has increased on this test, I wouldn’t focus too much on that. The numbers are still in the lowest part of the reference range. Make sure you focus on the basics. Perhaps you could help me by scoring the next items. Give yourself a 10 when you do these things really great and a 1 if you feel there is room for lots of improvements:
• Chewing until your food feels semi-liquid in your mouth
• Taking time to eat
• Eating without distractions like laptops, phones or other screens
• Eating sugar, flour products and other refined foods
• Going to bed on time
• Sleeping 7-8 hours
• Waking up with energyThese things are really basic but powerful!
Zonulin & ‘Leaky Gut’
You can’t really ‘heal’ zonulin. It is something that is produced for example by eating gluten. Perhaps you draw the conclusion of the presence of a leaky gut.Your intestinal barrier assessment from 25 January showed low serum zonulin. This test shows elevations of zonulin in the gut. Although there is some time between these tests, it supports the impression that zonulin is staying in the gut.
Do you know if you consumed wheat products before the test? Mild elevations of zonulin (like yours) in the gut can be present for very normal reasons (like eating wheat before the test). Interpretation of this one marker is not a strong case for the presence of a leaky gut. On the stool test, it would be best to asses the complete ‘intestinal health markers’ section.
sIgA is low, which can be caused by damage to the gut lining. But stress can lower immune function as well, just like low vitamin D.
The test didn’t detect parasites, worms, yeast, which are also good signs. But some imbalanced bacterial markers do point to there might be leaky gut present to a certain degree.
What could you do?
Try to focus on what you feel. If avoiding gluten makes your symptoms less, try to avoid them. If you believe you aren’t eating gluten, you could replace rice and see if you feel better without rice. Things you eat a lot of can lead to food sensitivities. Food sensitivities can also influence gut barrier function.Secretory IgA
Your thought of trying IGG was a good one. If you are sensitive to milk however this could cause some side effects. Do you know if you are sensitive to milk products? -
please update us on your investigations with mold at home.
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hello. Unfortunately, they still haven’t come in. Despite chasing them. Not much of an update.
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I would keep pushing. Dr. Jill Crista, a leading authority on mold & mycotoxin illness is our guest today at 6pm Dubai time for a live Q&A. I think it can be very valuable for you to join live. If not, please leave any questions for her under her event in the Event Calendar space.
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. I certainly will. I have a CBT session at 2.00pm my time for an hour. I will leave questions in stead.
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Hi Daniel,
Give yourself a 10 when you do these things really great and a 1 if you feel there is room for lots of improvements:
Chewing until your food feels semi-liquid in your mouth – 3 My food is very soft. I can’t chew for long.
Taking time to eat – 1. I am in paincramps whilst eating in the abdominal region. I just want to stop eating quickly.
Eating without distractions like laptops, phones or other screens – 10
Eating sugar, flour products and other refined foods 4 – I was due to sugar craving, comfort eating, breaking down as no improvement over the past 6 years.
Going to bed on time – 1. Delayed food emptying preventing me from going to bed.
Sleeping 7-8 hours – 10 but get up during the night due to heartburnreflux.
Waking up with energy – 1. Constant discomfort as soon as I get out of bed is soul destroying.
Secretory IgA
I haven’t had dairy for six years. I maybe sensitive now. To be honest with the leaky gut and MCAShistamine issues, I appear to be sensitive to everything.If I retry IgG Select – 75g, when is the best time to take it?
Zonulin
Increase in Zonulin must be due to the sugar craving foods I had been eating.No wheat, but maybe the biscuits contained wheat or other sweet foods I had.
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