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Histamine Retest
Hi B and Daniel,
How much is Histamine DAO test and how does it compare to the test by Regenerus Labs which I’ve done in the past.
I wan to check whether my histamine levels are normal now?
Nordic Lab (nordiclabs.com) v Advanced Intestinal Barrier Assessment – Regenerus Labs
The Nordics test is called the Histamine DAO. I’m not sure what is THAK.
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5 Replies
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Hey ,
The THAK test (or THDC in English, which stands for Total Histamine Degradation Capacity) is a measure of the total histamine degradation capacity.
What it tests is how well you are able to break down histamine. The good thing about the test is that it is done in a way that is independent of what enzyme (DAO, HMNT) histamine is degraded by.
It is a relatively new test. I think the test has potential, but the amount of research I could find on it was limited (click here if you like to learn more)
The benefits of the test from Regenerus are that
• It returns more information. For example, it reveals antibodies that elevate in your serum when LPS has entered your body.
• It measures serum zonulin.
• It measures your absolute histamine – which was high on your previous results. It would be interesting to know those values when you have low exposure to dietary histamine. High histamine values will translate into a low THAK since the amount of histamine can’t be degraded that fast compared to the number of histamine degrading enzymes produced by the body.
• Although it doesn’t measure the HMNT enzyme which helps break down histamine, it would be useful to compare your old DAO enzyme production to your current DAO enzyme production. This could help us see if your enzyme production has changed for some reason.It becomes a matter of preference. My personal choice would probably be the Regenerus test.
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I have stopped high histamine foods since the beginning of the year, but the refined sugar may not help. I have days where I am fine but then the low mood causes me to revert.
My DAO was fine then, BUT HMNT isn’t measured.
Thank you for explaining the Nordics Lab v Regenerus.
My zonnulin was high in the GI MAP from March 2023.
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Hey ,
I just wanted to let you know, after a discussion with Bernadette, I changed my mind a bit on the THAK test.
From a scientific point of view, the THAK test can’t differentiate well between the next 2 situations:
• high histamine levels with normal DAO and HMNT enzyme production and
• normal histamine levels with low DAO and HMNT enzyme production.This is why I preferred the other test. However…
In both situations, we would make the same lifestyle & supplement recommendations.
Since the THAK test is cheaper and if histamine is your main concern, the THAK test would be good.
You could use the money to invest in a new pan 🙂
Sorry if I confused you!
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It’s OK. I will go with intestinal permeability test as it will give a true comparison from the previous results.
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Hi Daniel,
I had a blood withdrawal to repeat the intestinal permeability test (leaky gut) which will also check for DAO, histamine intolerance and LPS etc…
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