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Blood test results
Hi B, Daniel and everyone. Could you please look into these results and let me know your comments?
Female 49 years old (relative) her neutrophils always come a bit below range.
Please note the 12 days before the blood test she had colds. Scratchy throat and sneezing but nothing major. -
12 Replies
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Hi
If I may share my thoughts only by the markers run and without knowing any of her symptoms,
I would say that seeing her WBC low together with the pattern of low Neutrophils and high Lymphocytes (hers only slightly above optimal range) usually indicate a (chronic) bacterial infection. Seeing the Monocytes elevated as well, could confirm the chronic infection.
With active infections (you mentioned few days prior to the test she had a cold) you typically see pattern of low WBC with high Monocytes, too.
Her RDW is slightly elevated.
With regards to her high Glucose, I would want to know if her blood was drawn in a fasted state? If she has her menstrual cycle and if so, in which phase she was when doing the test.
According to those answers, I would then like to see her Insulin as well as her HgBA1C to rule out blood sugar issues.
Her Globulin is slightly above optimal range and without knowing any of her symptoms it’s hard to pinpoint a direction here.
Total Protein is slightly above optimal range which can be an indicator for cellular dehydration.
All other liver markers look good to me.
I would maybe try to find out next what is taxing her immune system.
Cannot wait to read B’s and Daniel’s thoughts. -
hi there. No symptoms, but had major stress few months ago.
Glucose most probably from stress, she’s on low/moderate carbs diet, exercise regularly since 3 weeks, insulin and HbA1c all were optimal two months ago except for fasting glucose which why I think it’s stress results.Lately she started for first time in her life to take creatine before workout about 2-3 g
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oh, and she’s menstruating regularly. May I ask what is the connection here?
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women during their luteal phase may experience some insulin resistance. And if she had her blood drawn during that period, I thought maybe it could explain the higher glucose.
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Do you suspect the creatine supplementation is influencing any of her markers?
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it always helps to have more information, especially symptoms to help tie together labs with the unique individual. asked some astute questions about the timing of the test, especially that fasting glucose is suboptimally high which could be an indicator of insulin resistance.
You mentioned fasting insulin and HbA1c were measured previously. Do you have those results you can share? The reason why I’m asking is because “normal” is far from optimal, and there seems to be a picture of possible oxidative stress – maybe from blood sugar dysregulation, perhaps toxicity? It’s hard to say with no other information.
Her total bilirubin, although it’s within the reference range, is actually suboptimal low. Bilirubin is a waste product from the breakdown of red blood cells, and is what gives stool its brown color. It’s also a powerful antioxidant and low level could point to a few areas to explore.
We need zinc to make biliverdin enzyme which converts into bilirubin. So a lower bilirubin can be due to low zinc. Also lower total bilirubin is associated with elevated oxidative stress states because the body will use/recycle bilirubin to serve as an antioxidant to fight the oxidative stress! The suboptimal higher globulin can also point to the same picture of oxidative stress and higher free radical activity. There are many possible sources of oxidative stress, with sustained elevated blood sugar being one of them. There are many others too…
• Sustained elevated blood sugar (i.e. desired fasting insulin~5 mIU/L; HbA1c < 5.3%) • too much exercise, type-A personalities/being overworked. • Intake of processed and/or damaged fats (e.g. typical refined, Omega-6 vegetable oils, trans fats) I recommend only coconut oil (for cooking), butter or ghee (if dairy well-tolerated), and cold-pressed olive oil (for room-temp and low-heat use). • Many carcinogens (e.g. pesticides) & toxins such as heavy metals (e.g. arsenic, mercury***), mold & mycotoxins. • When sugar molecules are cooked until “browned”, advanced glycation end products (AGEs) form which are powerful creators of oxidative stress (e.g. in blood vessels).• Externally: over-cooking, browning, and cooking foods at high temperatures. Marinating meats and cooking lightly helps greatly in reducing AGE formation. • Internally: out-of-control diabetes creates AGEs inside our blood vessels. • Sustained inflammation in the body generates oxidative stress. And then higher oxidative stress generates more inflammation. And so on... But it can be reversed! Her liver enzymes, although they look optimal here, I am actually suspicious if it's being masked by an underlying vitamin B6 deficiency or insufficiency. These enzymes are highly dependent on B6, so a deficiency will mask what's really going on with the liver. Having a full picture of a person's symptoms, lifestyle and health history would help tie the picture better. There is however a pattern of possible dehydration given the suboptimal high protein, albumin and RBC values. Remind her to hydrate - not only with water, but with electrolytes as well if she's not. Her subotpimal low (almost clinically low) WBC and pattern of low Neutrophils and high Lymphocytes, points to the immune system struggling with a viral load. This could be acute or chronic, however since you mentioned that she's always wrestled with lower neutrophils, I'd be curious to see if there's a pattern of lower WBC as well in previous labs. Given the little information that's been presented, I would potentially look at sources of oxidative stress that may be taxing her immunity. Also look into the status of immune nutrients vitamins A, D, and RBC zinc (and copper) to make sure these are optimal. Hope this helps offer some direction to look into. Please invite them to join B Better as well so that we can better help guide them. -
I re checked my papers and this is what I used for the Neutrophils/Lymphocytes pattern:
*high neutro + low lymphs = chronic viral most often*
*Iow neutro + high lymphs = chronic bacterial most often*
Looks like that is is not accurate and I will look into it ☺️ -
neutrophils are the white blood cells used to fight off bacterial or pyrogenic infections, so an elevation usually points to a bacterial infection although that’s not the only possibility.
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and that is exactly what I had in my notes from way back from Dr Jess:
Neutrophils fight bacteria
Lymphocytes fight viruses
I get there -
thank you B. I love your brain! So, she was on day 7 of her cycle when this was done. Also, I just learned she takes 2.5mg anti thyroid medication for hyperthyroidism(levels in range that’s why low dose) and now I know the neutrophils could be lower because of this medicine. Right?
I’ll attached her CBC from January this year. As I said her results now were 12 days post infection (cold) and first time she has neutrophils absolute not in range.
Usually neutrophils and lymphocyte ratio are the problem and always WBC on lower side of normal. B, do you also believe that lymphocyte to neutrophils optimal ratio should be 1:2? And from your second comment the relation between high neutrophils and bacteria also high lymphocyte and virus so here in the first results in the post it’s showing virus. What about the results I attached now? Low neutrophils and normal to high lymphocytes?Definitely she’s dehydrated.
Also stressed.In July her fasting insulin was 5.2 (3-17)
Glucose fasting 96
Insulin resistance 1.35 (<2.10)
[IMG_7871.jpeg] -
was an HbA1C also measured?
With a clinically low neutrophil and lower WBC, this points to a chronic viral challenge. Lymphocytes are more “specialized forces” that can handle viruses. The latest result with clinically high Lymphocytes is proof her body was trying to fight off an active viral infection. Perhaps a reactivation? Or another virus?
Regarding the N-to-L ratio. In 2020, this study came out showing that higher NLRs and age were significantly associated with Covid illness severity.
In general, neutrophils should be much higher than lymphocytes but this 1:2 ratio was being used to assess illness severity risk.
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no HbA1c and I’m surprised honestly. Regarding the latest lymphocytes results as I said the blood was drawn after 12 days from being sick I don’t know if it was covid or not but it was mild. And she didn’t have severe covid previously. I think in her case ficus should be on oxidative stress and stress management
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