• Daniel

    Member
    March 22, 2023 at 9:17 pm

    Hey ,

    ACTH & Cortisol
    Cortisol levels are regulated in a feedback loop. If cortisol is low in the body, the hypothalamus in the brain will sense this and will send a hormone called CRH to the pituitary to make more ACTH. ACTH then tells the adrenals to make cortisol. Once cortisol rises, the hypothalamus will produce less CRH and the cortisol production reduces.

    When ACTH is high and cortisol is normal it generally means that your adrenals only produce enough cortisol under increased ACTH stimulation. Either the production in the adrenals is impaired or cortisol is removed from circulation.

    The adrenals can be impaired by genes for example with a condition called Congenital adrenal hyperplasia. This can also increase testosterone production since ACTH regulates androgens. But it depends on the elevations in ACTH. Does she experience symptoms of high testosterone, like:
    • Acne
    • facial hair growth
    • Abnormal menstruation
    • Male pattern baldness (Androgenic alopecia)
    • Infertility
    • Deepening of the voice

    A little damage to the adrenals can also give the same clinical picture. The adrenals might struggle with cortisol production and now the pituitary is actually ‘yelling’ to the adrenals: go make cortisol!
    It can also be that your adrenal function is normal, but cortisol is being broken down fast by liver enzymes for example by genetics. It might also be that cortisol is more bound to Cortisol Binding Globulin (CBG). Reasons, why CBG can be elevated, are for example:
    • Oral contraceptives or estrogen imbalances
    • Inflammation to the liver from for example with chronic active hepatitis (click here if you like to see the research).

    Perhaps you could share with us a little more details about your client so we can help you with more targeted advice. Things that can help us:
    • What type of test was done? Was a DUTCH test done as well? And if it was a blood draw it is important to know when? In the morning it is normal to have higher ACTH and cortisol. It might have led to mild elevations in ACTH but normal cortisol levels as a result. Even excitement for the test could increase ACTH mildly, while cortisol levels usually respond later.
    • What symptoms does she experience?
    • Is she on any medications?
    • Does she experience any high cortisol or low cortisol symptoms (Here you can find signs & symptoms of high and low cortisol)? It is important to know since she might have had normal cortisol levels at her blood draw, but that only tells you about her stress levels at the time.

    Detoxify Mold
    Have you seen the recording of our guest speaker dr. Jill Crista on mold? You can find the recording here. I’m sharing this since the first priority in removing mold in your life is removing the source. Supplements that can help you with mold detoxification are broad-spectrum anti microbial like Candibactin AR and Candibactin BR. Other anti microbial supplements that can help are biocidin from biocidin botanicals.

    You should also work with binders like GI Detox to prevent the herxheimer reaction. I know Bernadette is almost done with filming her mold course, so there will be much more information on this topic available soon.

    I hope this will help!

  • ranakolankiewicz

    Member
    March 23, 2023 at 6:55 am

    she’s my sister, my job is far from this area 🙂 she tried to search about high ACTH and always came with either low or high cortisol but hers was normal. The dr wants her on antidepressants and she’s not depressed 🙂 she has anxiety sometimes but I think it’s from mold poisoning. She did Dutch test but I have no clue what is it or what was there. But I know all results came in the green.

    Thanks for your insight. Very interesting info.

  • Daniel

    Member
    March 24, 2023 at 8:57 pm

    Hey  

    It would still be interesting to take a look at the DUTCH test, even if all the markers are in the green. Feel free to upload the results if she feels like sharing them!

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